Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657580 | 0.92 | ROCK2 (0.48) | CYP11B1CYP11B2ROCK2PIM1PIM3 | |
| SCHEMBL6845970 | 0.90 | HTR1D (0.48) | CYP11B1CYP11B2ROCK2PIM1PIM3 | |
| SCHEMBL6846125 | 0.88 | CYP11B2 (0.59) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 | |
| SCHEMBL6657591 | 0.85 | CYP11B2 (0.56) | CYP11B1CYP11B2PIM1CYP19A1CYP17A1 | |
| SCHEMBL6657897 | 0.85 | CYP11B2 (0.55) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 | |
| SCHEMBL6847800 | 0.85 | CYP11B2 (0.51) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 | |
| SCHEMBL6662535 | 0.84 | CYP19A1 (0.51) | CYP11B1CYP11B2ROCK2PIM1PIM3 | |
| SCHEMBL22515743 | 0.82 | CYP11B2 (0.53) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 | |
| SCHEMBL6844281 | 0.82 | CYP11B2 (0.57) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 | |
| SCHEMBL6655119 | 0.81 | CYP11B2 (0.51) | CYP11B1CYP11B2CYP19A1CYP17A1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | CYP11B1 30/4885CYP11B2 53/4885ROCK2 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.