Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.70 |
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | HTT | P42858 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.68 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684645 | 0.92 | MEN1 (0.72) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL8290634 | 0.86 | MAPT (0.67) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL684612 | 0.86 | MEN1 (0.72) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL685193 | 0.83 | MAPT (0.67) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL6570259 | 0.83 | NPC1 (0.77) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6570260 | 0.83 | NPC1 (0.77) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL685119 | 0.83 | NPC1 (0.77) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13780402 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL684936 | 0.81 | SIRT1 (0.67) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL15917585 | 0.80 | NPC1 (0.70) | MEN1KMT2AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | MEN1 536/4885KMT2A 1362/4885MAPT 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.