Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851801 | 0.82 | CA1 (0.49) | CA1CA2 | |
| SCHEMBL6850444 | 0.77 | EGFR (0.68) | TSHRFLT1FLT4KDRCA1 | |
| SCHEMBL6850555 | 0.75 | FBP1 (0.62) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL3929742 | 0.75 | PTGES2 (0.49) | HSD17B10CA1CA2 | |
| SCHEMBL6846253 | 0.75 | GAA (0.52) | MCL1HPGDTSHRMAPK1RAB9A | |
| SCHEMBL6259655 | 0.74 | MCL1 (0.66) | MCL1HPGDTSHRMAPK1RAB9A | |
| SCHEMBL15896258 | 0.74 | MCL1 (0.62) | MCL1HPGDTSHRMAPK1RAB9A | |
| SCHEMBL6849945 | 0.73 | CA1 (0.54) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL8789596 | 0.73 | MAPK1 (0.55) | MCL1HPGDTSHRMAPK1RAB9A | |
| SCHEMBL9577232 | 0.73 | GAA (0.69) | MCL1HPGDTSHRMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |