Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789596 | 0.86 | MAPK1 (0.55) | GAAMCL1HPGDPOLBTSHR | |
| SCHEMBL6851806 | 0.82 | ATM (0.47) | GAAPOLBTSHRMAPK1HSD17B10 | |
| SCHEMBL9577232 | 0.80 | GAA (0.69) | GAAMCL1HPGDPOLBTSHR | |
| SCHEMBL3717918 | 0.78 | GAA (0.67) | GAAMCL1HPGDPOLBTSHR | |
| SCHEMBL6850445 | 0.77 | MEP1B (0.62) | TSHRALDH1A1 | |
| SCHEMBL28582158 | 0.77 | GAA (0.57) | GAAMCL1HPGDPOLBTSHR | |
| SCHEMBL7598374 | 0.76 | NPC1 (0.47) | POLBALDH1A1 | |
| SCHEMBL4029646 | 0.76 | WDR5 (0.48) | GAAPOLBALDH1A1GSTO1 | |
| SCHEMBL9577219 | 0.76 | GAA (0.73) | GAAMCL1HPGDPOLBTSHR | |
| SCHEMBL6850559 | 0.75 | KAT6A (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |