Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | FLT1 | P17948 | 2/20 | 0.50 |
| ▸ | FLT4 | P35916 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.46 |
| ▸ | FBP1 | P09467 | 6/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850555 | 0.83 | FBP1 (0.62) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL6850444 | 0.82 | EGFR (0.68) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL10029345 | 0.76 | CA1 (0.55) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL9887819 | 0.76 | FLT1 (0.54) | FLT1FLT4KDRFABP4FBP1 | |
| SCHEMBL6849915 | 0.75 | CA1 (0.58) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL3928657 | 0.74 | CA1 (0.67) | CA1CA2EGFRERBB2 | |
| SCHEMBL6851801 | 0.74 | CA1 (0.49) | CA1CA2 | |
| SCHEMBL6846252 | 0.73 | MCL1 (0.51) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL4464537 | 0.73 | CA1 (0.70) | CA1CA2EGFRERBB2FBP1 | |
| SCHEMBL6849946 | 0.71 | FABP4 (0.55) | FLT1FLT4KDRFABP4ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |