Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169839 | 0.75 | KDM4E (0.37) | ESR1ESR2ALOX15CASP1 | |
| SCHEMBL15984630 | 0.70 | ALDH1A1 (0.40) | CYP3A4CASP1RECQL | |
| Ammonia Solution, Strong SCHEMBL28938938 | 0.48 | CYP1A2 (0.47) | ALOX15CYP3A4CASP1RECQL | |
| SCHEMBL31290737 | 0.48 | ALDH1A1 (0.64) | ESR1ESR2CYP3A4 | |
| SCHEMBL31731083 | 0.48 | ALDH1A1 (0.64) | ESR1ESR2CYP3A4 | |
| SCHEMBL4969576 | 0.46 | — | — | |
| SCHEMBL2468018 | 0.46 | ALDH1A1 (0.90) | CYP3A4 | |
| Naphthalene SCHEMBL8613802 | 0.41 | CYP2A6 (1.00) | CYP3A4 | |
| SCHEMBL58152 | 0.41 | MEN1 (0.61) | ALOX15CYP3A4RECQL | |
| Naphthalene SCHEMBL8953 | 0.41 | CYP2A6 (1.00) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498797-A | Pyrrolo- [2,1,5-cd] indolizine cyclics and its synthetic method | UNIV GUANGDONG PHARM | 2019-11-26 | — | — | CN | claimed |
| CN-108101906-A | A kind of preparation method of cyclopenta [f] pyrrolo- [2,1,5-cd] indolizine derivative | 太原理工大学 | 2018-06-01 | — | — | CN | claimed |
| US-20260114114-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS | MERCK PATENT GMBH (DE) | 2026-04-23 | — | — | US | disclosed |
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | MERCK PATENT GMBH (DE) | 2026-02-24 | — | — | US | disclosed |
| WO-2025025941-A1 | SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC CARBOXYLATE ESTER COMPOUND, AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2025-02-06 | — | — | WO | disclosed |
| EP-3633702-B1 | METHOD FOR MANUFACTURING CONDUCTIVE POLYMER SOLID ELECTROLYTIC CAPACITOR, AND CONDUCTIVE POLYMER | SOKEN KAGAKU KK (JP) | 2024-11-20 | — | — | EP | disclosed |
| CN-117177741-A | Combination of norepinephrine reuptake inhibitors and cannabinoids for the treatment of sleep apnea | 爱普宁公司(特拉华) | 2023-12-05 | — | — | CN | disclosed |
| CN-117062626-A | Methods and compositions for treating sleep apnea | 爱普宁公司(特拉华) | 2023-11-14 | — | — | CN | disclosed |
| EP-4271160-A2 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | Merck Patent GmbH (DE) | 2023-11-01 | — | — | EP | disclosed |
| US-11773276-B2 | Conductive polymer composition | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| EP-3257850-B1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | MERCK PATENT GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| EP-0986560-B1 | PYRROLO 2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | KAROBIO AB (SE) | 2004-03-24 | — | — | EP | disclosed |
| US-6080754-A | Pyrrolo[2,1,5-cd]indolizine derivatives useful in the prevention or treatment of estrogen related diseases or syndromes | NOVO NORDISK A/S (DK) | 2000-06-27 | — | — | US | disclosed |
| US-6080754-A | Pyrrolo[2,1,5-cd]indolizine derivatives useful in the prevention or treatment of estrogen related diseases or syndromes | NOVO NORDISK A/S (DK) | 2000-06-27 | — | — | US | disclosed |
| US-6075036-A | Pyrrolo [2,1,5-cd] indolizine derivatives useful in the prevention or treatment of estrogen related diseases or syndromes | NOVO NORDISK (DK) | 2000-06-13 | — | — | US | disclosed |
| EP-0988303-A1 | PYRROLO 2,1,5-cd]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 2000-03-29 | — | — | EP | disclosed |
| EP-0986560-A1 | PYRROLO 2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055483-A9 | PYRROLO[2,1,5-cd]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK AS (DK) | 2000-02-03 | — | — | WO | disclosed |
| WO-1998055483-A1 | PYRROLO[2,1,5-cd]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1998-12-10 | — | — | WO | disclosed |
| WO-1998055482-A1 | PYRROLO[2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | NR2E3, CDYL, TYR | ESR1 24/4885ESR2 5/4885ALOX15 2317/4885 |
| US-20260114114-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS | LEF1, AP2A1, CACNA2D1 | ESR1 156/4885ESR2 46/4885ALOX15 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.