Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703006 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GAAMMP2MMP12MAPK1 | |
| SCHEMBL1822255 | 0.77 | ENPP1 (0.47) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL1826067 | 0.72 | PPARG (0.46) | ALDH1A1GAAMAPK1L3MBTL1 | |
| SCHEMBL14434077 | 0.72 | MAOB (0.56) | MAPTMAOBPARP10ALDH1A1GAA | |
| SCHEMBL11526561 | 0.71 | L3MBTL1 (0.51) | MAPTHPGDALDH1A1GAALMNA | |
| SCHEMBL11589414 | 0.71 | CTDSP1 (0.44) | MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL13532220 | 0.71 | ACHE (0.46) | MAPTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL20523786 | 0.70 | KMT2A (0.45) | MAPTMAOBPARP10ALDH1A1MMP2 | |
| SCHEMBL11522867 | 0.70 | MAPT (0.48) | MAPTMAOBALDH1A1GAAMMP2 | |
| SCHEMBL24590268 | 0.70 | MAPT (0.38) | MAPTHPGDALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |