SCHEMBL6846969

SCHEMBL6846969

CCC(NC(C)(C)C)C(N)(CCCCN)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6844189 0.68 DNM1 (0.33) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14811431 0.65 DNM1 (0.39) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL10356313 0.64 NFKB1 (0.41) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL13513566 0.64 TSHR (0.35) TSHR
SCHEMBL5859130 0.63 NFKB1 (0.47) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL18400700 0.63 DNM1 (0.65) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14812266 0.63 DNM1 (0.43) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL7173780 0.62 DNM1 (0.41) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL12734931 0.62 DNM1 (0.41) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL829736 0.62 DNM1 (0.44) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed