SCHEMBL6844189

SCHEMBL6844189

CCCCNC(C)C(N)(CCCCN)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21800057 0.69 CA12 (0.39) DNM1MEN1KMT2ATSHR
SCHEMBL11922807 0.68 TSHR (0.36) MEN1KMT2AALDH1A1TSHR
SCHEMBL27387880 0.68 TSHR (0.36) MEN1KMT2AALDH1A1TSHR
SCHEMBL9639778 0.68 GNAI3 (0.36) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6846969 0.68 DNM1 (0.32) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL29243954 0.67 ALDH1A1 (0.39) MEN1KMT2AALDH1A1TSHREPHX1
SCHEMBL21799582 0.67 PAOX (0.38) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21799632 0.67 PAOX (0.38) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21799741 0.67 PAOX (0.38) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21799874 0.67 PAOX (0.38) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed