Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13562529 | 0.83 | LMNA (0.47) | EGFRLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL13517617 | 0.83 | OPRM1 (0.52) | EGFRLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL6847843 | 0.82 | TMEM97 (0.46) | EGFRLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL13517749 | 0.82 | MAPT (0.51) | EGFRKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL13562742 | 0.80 | TSHR (0.65) | LMNAL3MBTL1ACHEBCHETSHR | |
| SCHEMBL13562641 | 0.79 | CYP1A2 (0.46) | EGFRLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL6847576 | 0.79 | KMT2A (0.51) | EGFRKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL14350189 | 0.77 | KMT2A (0.51) | KMT2AMEN1L3MBTL1HTTOPRM1 | |
| SCHEMBL13562673 | 0.77 | HSD11B1 (0.43) | EGFRLMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL11817593 | 0.76 | KMT2A (0.39) | LMNAKMT2AMEN1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055561-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE THEREOF | 独立行政法人科学技術振興機構 (JP) | 2011-05-12 | — | — | WO | disclosed |