Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27348845 | 0.86 | LMNA (0.50) | CYP1A2MAPK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28087618 | 0.84 | TSHR (0.52) | LMNAKMT2ATSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL4361110 | 0.80 | AKR1B1 (0.39) | LMNAKMT2ATSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL6854347 | 0.78 | KDM4A (0.38) | LMNAKMT2ATSHRNFKB1PMP22 | |
| SCHEMBL1202607 | 0.78 | TSHR (0.55) | LMNAKMT2ATSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL29098178 | 0.78 | CYP1A2 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNAKMT2A | |
| Adipic Acid SCHEMBL29098179 | 0.78 | CYP1A2 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNAKMT2A | |
| Succinic Acid SCHEMBL28153397 | 0.78 | CYP2C19 (0.48) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Adipic Acid SCHEMBL5597727 | 0.76 | CYP2D6 (0.40) | CYP1A2SMN1; SMN2LMNAKMT2ATSHR | |
| Adipic Acid SCHEMBL29021414 | 0.76 | CYP1A2 (0.61) | CYP1A2MAPK1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407585-B2 | Aqueous ink for ink jet recording, aqueous ink set for ink jet recording, and ink jet recording method | FUJI XEROX CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20180086930-A1 | AQUEOUS INK FOR INK JET RECORDING, AQUEOUS INK SET FOR INK JET RECORDING, AND INK JET RECORDING METHOD | FUJI XEROX CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |
| US-6800673-B2 | FOR A THERMAL, PIEZOELECTRIC, ELECTRIC FIELD OR ACOUSTIC INK JET RECORDING SYSTEM, EXCELLENT IN QUALITIES OF RECORDED IMAGES, SUPERIOR IN IMAGE WATER RESISTANCE AND IMAGE FASTNESS PROPERTIES AND EXCELLENT IN STABILITY OF INK | FUJI PHOTO FILM CO., LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| US-6734225-B2 | DISPERSION OF OIL-SOLUBLE DYE PARTICLES BASED ON A PYRAZOLO-(5,1-C)-S-TRIAZOLE OR PYRAZOLO(1,5-B) RING; STABILITY; COLORFASTNESS; WATERPROOFING; REPRODUCTION, ESPECIALLY MAGENTA; PRINTING ON PAPER; ANTIFOULING AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20020143079-A1 | Ink for ink jet recording, method of producing ink for ink jet recording,and ink jet recording method | FUJIFILM CORPORATION (JP) | 2002-10-03 | — | — | US | disclosed |
| US-20010020056-A1 | Coloring composition, ink for ink jet, and ink jet recording method | FUJIFILM CORPORATION (JP) | 2001-09-06 | — | — | US | disclosed |