Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27348845 | 0.87 | LMNA (0.50) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL28087618 | 0.85 | TSHR (0.52) | LMNATSHRNFKB1PMP22CYP2C19 | |
| Adipic Acid SCHEMBL4361110 | 0.81 | AKR1B1 (0.39) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL1202607 | 0.79 | TSHR (0.55) | LMNATSHRNFKB1PMP22PPARG | |
| Succinic Acid SCHEMBL28153397 | 0.79 | CYP2C19 (0.48) | LMNATSHRNFKB1PMP22CYP2C19 | |
| Adipic Acid SCHEMBL6847194 | 0.78 | CYP1A2 (0.44) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Malonic Acid SCHEMBL17963021 | 0.75 | CYP2C19 (0.48) | LMNATSHRCYP2C19ALDH1A1 | |
| Adipic Acid SCHEMBL5597727 | 0.74 | CYP2D6 (0.40) | KDM4AKDM4CLMNATSHRNFKB1 | |
| Adipic Acid SCHEMBL5555748 | 0.73 | GPR84 (0.54) | KDM4AKDM4CLMNAADRA1ATSHR | |
| SCHEMBL693740 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713528-B2 | AQUEOUS DISPERSION OF NONIONIC OIL SOLUBLE POLYMER AND HYDROPHOBIC HIGH BOILING POINT ORGANIC SOLVENT; WATER AND LIGHT RESISTANCE; PERMEABILITY; NONSTAINING; COLOR DURABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| US-20030222959-A1 | AQUEOUS DISPERSION OF NONIONIC OIL SOLUBLE POLYMER AND HYDROPHOBIC HIGH BOILING POINT ORGANIC SOLVENT; WATER AND LIGHT RESISTANCE; PERMEABILITY; NONSTAINING; COLOR DURABILITY | FUJIFILM CORPORATION (JP) | 2003-12-04 | — | — | US | disclosed |
| US-20010036979-A1 | Coloring composition, ink-jet ink and ink-jet recording method | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-01 | — | — | US | disclosed |