Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847255 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL5021599 | 0.80 | ADORA2B (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL15743132 | 0.78 | ADORA2A (0.33) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6751928 | 0.78 | ADORA2B (0.35) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL473734 | 0.77 | ADORA2A (0.32) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7862548 | 0.76 | PNP (0.30) | PNP | |
| SCHEMBL2249841 | 0.74 | HPRT1 (0.37) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL16106177 | 0.73 | ADORA2A (0.37) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL5664356 | 0.72 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL874734 | 0.72 | ADORA2A (0.45) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372664-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | Hollis-Eden Pharmaceuticals Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002069977-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2002-09-12 | — | — | WO | disclosed |