Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | CDK1 | P06493 | 6/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | MGMT | P16455 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266585 | 0.84 | CDK1 (0.40) | PDE4APDE4BPDE4CPDE4DCDK1 | |
| SCHEMBL6847248 | 0.81 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL2385930 | 0.80 | ADORA2B (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL15743135 | 0.78 | CDK1 (0.42) | PDE4APDE4BPDE4CPDE4DCDK1 | |
| SCHEMBL6751932 | 0.78 | PNP (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL5503610 | 0.77 | CDK1 (0.42) | PDE4APDE4BPDE4CPDE4DCDK1 | |
| SCHEMBL8214982 | 0.76 | XDH (0.45) | PDE4APDE4BPDE4CPDE4DCDK1 | |
| SCHEMBL441798 | 0.75 | DPP4 (0.44) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16098082 | 0.73 | PNP (0.37) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL28237494 | 0.73 | DPP4 (0.42) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104093830-A | Clonal strains of attenuated vaccinia virus and methods of use thereof | GENELUX CORP | 2014-10-08 | — | — | CN | disclosed |
| EP-1372664-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | Hollis-Eden Pharmaceuticals Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002069977-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2000006573-A1 | ANTIVIRAL ALKYL SUBSTITUTED PURINE DERIVATIVES AND THEIR PREPARATION | Kemijski inštitut (SI) | 2000-02-10 | — | — | WO | disclosed |