Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11988035 | 0.85 | AVPR1A (0.45) | ALDH1A1KMT2AKDM4EL3MBTL1NR3C1 | |
| SCHEMBL25919180 | 0.83 | ALOX12 (0.47) | MDM2ALOX12GRM1ALDH1A1KMT2A | |
| SCHEMBL19041698 | 0.80 | CYP11B2 (0.53) | MDM2CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6655119 | 0.76 | CYP11B2 (0.51) | CYP11B1CYP11B2CYP19A1CYP17A1GRM1 | |
| SCHEMBL15159281 | 0.75 | CYP1A2 (0.45) | MDM2CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL30118223 | 0.75 | CYP1A2 (0.43) | MDM2CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL21068920 | 0.75 | CYP1A2 (0.43) | MDM2CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL22515748 | 0.74 | CYP11B2 (0.49) | CYP11B1CYP11B2CYP19A1CYP17A1GRM1 | |
| SCHEMBL19041604 | 0.74 | CYP1A2 (0.44) | MDM2CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6844269 | 0.73 | SCN2B (0.49) | MDM2CYP11B2ALOX12GRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | MDM2 542/4885CYP11B1 30/4885CYP11B2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.