Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847516 | 0.83 | MDM2 (0.45) | ALOX12KMT2AGRM1MAPTALDH1A1 | |
| SCHEMBL28062439 | 0.82 | MAT2A (0.53) | ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL30446730 | 0.81 | ALDH1A1 (0.55) | SLC6A2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1885602 | 0.81 | ALDH1A1 (0.55) | SLC6A2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL64405 | 0.79 | ALDH1A1 (0.44) | SLC6A2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13425012 | 0.79 | ALDH1A1 (0.47) | SLC6A2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13483671 | 0.79 | TSHR (0.43) | SLC6A2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL12091794 | 0.78 | AOC3 (0.52) | ALOX12KMT2AALDH1A1CYP3A4MDM2 | |
| SCHEMBL11000240 | 0.77 | ALOX12 (0.41) | ALOX12GSRKMT2AMAPTALDH1A1 | |
| SCHEMBL11005039 | 0.77 | CYP19A1 (0.49) | ALOX12GSRALDH1A1GFERNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242557-A9 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | Kineta, Inc. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242557-A9 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | PSMG3, PSMB1, PSMC1 | ALOX12 1828/4885GSR 986/4885SLC6A2 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.