Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747047 | 0.91 | PPARG (0.50) | PPARGSAE1UBA2MAPTMEN1 | |
| Hydroxyamine SCHEMBL5794204 | 0.90 | MCL1 (0.46) | PPARGSAE1UBA2MAPTMEN1 | |
| SCHEMBL5794208 | 0.89 | PPARG (0.43) | PPARGSAE1UBA2MAPTMEN1 | |
| SCHEMBL5746559 | 0.85 | PPARG (0.51) | PPARGMEN1KMT2ALMNAHTT | |
| SCHEMBL5745179 | 0.85 | THRB (0.47) | PPARGLMNAHTTMCL1GAA | |
| SCHEMBL5746552 | 0.84 | HIF1A (0.45) | MEN1KMT2ALMNAHTTMCL1 | |
| SCHEMBL5747698 | 0.84 | PPARG (0.45) | PPARGLMNAHTTMCL1GAA | |
| SCHEMBL5746821 | 0.82 | LMNA (0.53) | LMNAHTTTSHR | |
| SCHEMBL5745670 | 0.82 | PPARG (0.52) | PPARGMAPTMEN1KMT2ALMNA | |
| SCHEMBL5745464 | 0.81 | GAA (0.41) | PPARGMAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1173427-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063197-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-10-26 | — | — | WO | disclosed |