Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746660 | 0.91 | PPARG (0.48) | HIF1APDE5AACHELMNAHTT | |
| SCHEMBL5746821 | 0.85 | LMNA (0.53) | LMNAHTTTSHRHDAC6HDAC8 | |
| SCHEMBL6847542 | 0.84 | BMP1 (0.40) | LMNAHTTTSHRMEN1KMT2A | |
| SCHEMBL5746559 | 0.84 | PPARG (0.51) | LMNAHTTTHRBTSHRHDAC6 | |
| SCHEMBL5745179 | 0.84 | THRB (0.47) | LMNAHTTTHRBTSHRMCL1 | |
| SCHEMBL5747698 | 0.83 | PPARG (0.45) | LMNAHTTTHRBSMN1; SMN2MCL1 | |
| SCHEMBL6841912 | 0.82 | RAB9A (0.45) | LMNAHTTTHRBTSHRSMN1; SMN2 | |
| SCHEMBL5745464 | 0.79 | GAA (0.41) | LMNAHTTTSHRHDAC6HDAC8 | |
| SCHEMBL6846303 | 0.79 | GAA (0.49) | LMNAHTTHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL6847051 | 0.78 | PPARG (0.43) | LMNAHTTTHRBTSHRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1173427-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063197-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-10-26 | — | — | WO | disclosed |