Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | MTOR | P42345 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KDM1A | O60341 | 3/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | OGG1 | O15527 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049960 | 0.87 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2MTORCYP1A2 | |
| SCHEMBL683725 | 0.85 | KDM1A (0.67) | NPC1RAB9ASMN1; SMN2MTORKDM1A | |
| SCHEMBL684817 | 0.85 | KDM1A (0.79) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL684658 | 0.84 | KDM1A (0.83) | NPC1RAB9ASMN1; SMN2MTORCYP1A2 | |
| SCHEMBL12316802 | 0.84 | KDM1A (0.65) | NPC1RAB9ASMN1; SMN2MTORKDM1A | |
| SCHEMBL684535 | 0.84 | KDM1A (0.65) | NPC1RAB9ASMN1; SMN2MTORKDM1A | |
| SCHEMBL684473 | 0.84 | MTOR (0.77) | NPC1RAB9ASMN1; SMN2MTORCYP1A2 | |
| SCHEMBL684771 | 0.84 | KDM1A (0.70) | RAB9ASMN1; SMN2MTORCYP1A2CYP3A4 | |
| SCHEMBL684684 | 0.83 | KDM1A (0.72) | NPC1RAB9ASMN1; SMN2MTORCYP1A2 | |
| SCHEMBL12387768 | 0.82 | KDM1A (0.74) | NPC1RAB9ASMN1; SMN2MTORKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | NPC1 1690/4885RAB9A 3846/4885SMN1; SMN2 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.