SCHEMBL6847846

SCHEMBL6847846

CCCCOC(=O)OC=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.54
ALDH1A1 P00352 1/20 0.52
TSHR P16473 5/20 0.50
HPGD P15428 1/20 0.50
HCAR2 Q8TDS4 3/20 0.47
NAAA Q02083 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EPHX1 P07099 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 1/20 0.39
RNASEL Q05823 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1115645 0.94 NAAA (0.50) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL27841060 0.92 NAAA (0.53) ATMALDH1A1TSHRHCAR2NAAA
SCHEMBL1050435 0.86
SCHEMBL444270 0.83 ATM (0.54) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL37837 0.81 ALDH1A1 (0.67) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL5537440 0.81 TSHR (0.59) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL451520 0.81 ATM (0.52) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL27979299 0.81 ATM (0.52) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL450231 0.79 ATM (0.50) ATMALDH1A1TSHRHPGDHCAR2
SCHEMBL28758644 0.79 ALDH1A1 (0.64) ATMALDH1A1TSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-112313219-A 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors 辉瑞公司 2021-02-02 CN disclosed
US-8766019-B2 Method for separating butanol NANJING UNIVERSITY OF TECHNOLOGY (CN) 2014-07-01 US disclosed
US-20130158303-A1 METHOD FOR SEPARATING BUTANOL NANJING UNIVERSITY OF TECHNOLOGY (CN) 2013-06-20 US disclosed
CN-102002010-A Method for purifying bisoxazoline alkane compound SUMITOMO CO LTD 2011-04-06 CN disclosed
US-6692971-B2 QUALITATIVE AND QUANTITATIVE ANALYSIS IN BIOLOGICAL SAMPLES BY ESTERIFYING ACID AND USING TANDEM MASS SPECTROSCOPY USING ATMOSPHERIC PRESSURE IONIZATION TECHNIQUES IN THE POSITIVE MODE; DIAGNOSIS OF VITAMIN B12 DEFICIENCY UNIVERSITY OF UTAH RESEARCH FOUNDATION 2004-02-17 US disclosed
US-20020019056-A1 Method of analyzing dicarboxylic acids UNIVERSITY OF UTAH RESEARCH FOUNDATION 2002-02-14 US disclosed