Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530154 | 0.81 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL18241862 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL8554327 | 0.81 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL11900111 | 0.78 | KCNN4 (0.35) | TSHRKCNN4ALDH1A1 | |
| SCHEMBL18378491 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL5376223 | 0.77 | — | — | |
| SCHEMBL2093927 | 0.76 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL18378651 | 0.76 | TSHR (0.30) | TSHR | |
| SCHEMBL24702 | 0.75 | TSHR (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL3371 | 0.75 | TSHR (0.48) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | claimed |
| US-6509426-B2 | Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability | JAPAN POLYCHEM CORPORATION (JP) | 2003-01-21 | — | — | US | claimed |
| US-20010041794-A1 | Nucleotide analogs | GILEAD SCIENCES, INC. | 2001-11-15 | — | — | US | claimed |
| US-5798340-A | ANTITUMOR/ANTINEOPLASTIC ACTIITY, VIRICIDES; BROAD SPECTRUM MICROBIOCIDES; THIOPHOSPHONATES HYDROLYZABLE IN VIVO; ORAL ADMINISTRATION; BIOAVAILABILITY; NONTOXIC; POTENCY | GILEAD SCIENCES, INC. (US) | 1998-08-25 | — | — | US | claimed |
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | claimed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | claimed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | claimed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | claimed |
| EP-0079467-A1 | N-substituted O-pyrazol-4-yl-carbamic-acid esters, process for their preparation and their use as biocides | BAYER AG (DE) | 1983-05-25 | — | — | EP | claimed |
| EP-4305116-A1 | SILICON-BASED COMPOSITIONS AND APPLICATIONS THEREOF | Momentive Performance Materials Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| US-20240010786-A9 | POLYOL COMPOSITIONS | PRESIDIUM INNOVATIONS, LLC | 2024-01-11 | — | — | US | disclosed |
| US-11751472-B2 | Aromatic amine derivative and elecroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2023-09-05 | — | — | US | disclosed |
| US-11678571-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | IDEMITSU KOSAN CO., LTD. (JP) | 2023-06-13 | — | — | US | disclosed |
| US-20230055656-A1 | HYDROPHOBIC COATING COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-02-23 | — | — | US | disclosed |
| US-4326878-A | Herbicidal and plant-growth-regulating 1,2,4-trisubstituted-1,2,4-triazolidin-3,5-dithiones | CHEVRON RESEARCH (US) | 1982-04-27 | — | — | US | disclosed |
| US-4276420-A | PRE- AND POST-EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| US-4269856-A | AN N-TETRACHLOROETHYTHIO-SUBSTITUTED SULFONAMIDE; FUNGICIDES | CHEVRON RESEARCH COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4208348-A | MITICIDES | CHEVRON RESEARCH COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4107332-A | N-TETRACHLOROETHYLTHIO-SUBSTITUTED SULFONAMIDES | CHEVRON RESEARCH COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678571-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | RPS17, RPS19, CDK17 | TSHR 2347/4885CYP1A2 1066/4885KCNN4 411/4885 |
| US-20010041794-A1 | Nucleotide analogs | PNP, NUDT1, TYMP | TSHR 2855/4885CYP1A2 4728/4885KCNN4 2618/4885 |
| US-11751472-B2 | Aromatic amine derivative and elecroluminescence device using the same | ALK, ALKBH3, ACVRL1 | TSHR 2318/4885CYP1A2 286/4885KCNN4 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.