SCHEMBL6848009

SCHEMBL6848009

CCCCN(CCCC)OC(C)=O.CCOC(C)OCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
ALDH1A1 P00352 3/20 0.34
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CES1 P23141 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
HSD17B10 Q99714 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL886851 0.85 ALDH1A1 (0.44) LMNAALDH1A1CA12CA1CA9
SCHEMBL662739 0.82 LMNA (0.48) LMNAALDH1A1HSD17B10
SCHEMBL28535905 0.79 ALDH1A1 (0.43) ALDH1A1CA12CA1CA9CES1
SCHEMBL11316939 0.77 ALDH1A1 (0.41) ALDH1A1CES1HSD17B10
SCHEMBL11324311 0.77 ALDH1A1 (0.41) ALDH1A1CES1HSD17B10
SCHEMBL11317529 0.77 ALDH1A1 (0.41) ALDH1A1CES1HSD17B10
SCHEMBL190924 0.77 ALDH1A1 (0.41) ALDH1A1CES1HSD17B10
SCHEMBL6848043 0.76 LMNA (0.50) LMNAALDH1A1HSD17B10
1-Hexanol SCHEMBL29163470 0.75 ALDH1A1 (0.48) LMNAALDH1A1CES1HSD17B10
1-Heptanol SCHEMBL29163446 0.75 ALDH1A1 (0.48) LMNAALDH1A1CES1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210085633-A1 RIVASTIGMINE-CONTAINING TRANSDERMAL ABSORPTION PREPARATION TEIKOKU SEIYAKU CO., LTD. (JP) 2021-03-25 US disclosed
EP-3656383-A1 RIVASTIGMINE-CONTAINING PERCUTANEOUS ABSORPTION-TYPE PREPARATION Teikoku Seiyaku Co., Ltd. (JP) 2020-05-27 EP disclosed
US-20040028724-A1 Pharmaceutical preparation of percutaneous absorption type HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2004-02-12 US disclosed
EP-1340496-A1 PHARMACEUTICAL PREPARATION OF PERCUTANEOUS ABSORPTION TYPE HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2003-09-03 EP disclosed