SCHEMBL6848043

SCHEMBL6848043

CC(=O)ON(C)C.CCOC(C)OCC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662739 0.82 LMNA (0.48) LMNAALDH1A1HSD17B10TSHR
SCHEMBL5907461 0.80 LMNA (0.57) LMNAALDH1A1HSD17B10
Acetone SCHEMBL590699 0.79 LMNA (0.71) LMNAALDH1A1HSD17B10TSHR
Acetic Acid SCHEMBL23907968 0.77 LMNA (0.67) LMNAALDH1A1HSD17B10TSHR
Acetic Acid SCHEMBL222953 0.77 LMNA (0.67) LMNAALDH1A1HSD17B10TSHR
Butanedione SCHEMBL4368674 0.77 LMNA (0.67) LMNAALDH1A1HSD17B10TSHR
Butane SCHEMBL3151311 0.77 LMNA (0.52) LMNAALDH1A1HSD17B10
SCHEMBL156391 0.76
SCHEMBL6055619 0.76 LMNA (0.57) LMNAALDH1A1HSD17B10TSHR
Ethyl Acetate SCHEMBL9468886 0.76 ALDH1A1 (0.67) LMNAALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210085633-A1 RIVASTIGMINE-CONTAINING TRANSDERMAL ABSORPTION PREPARATION TEIKOKU SEIYAKU CO., LTD. (JP) 2021-03-25 US disclosed
EP-3656383-A1 RIVASTIGMINE-CONTAINING PERCUTANEOUS ABSORPTION-TYPE PREPARATION Teikoku Seiyaku Co., Ltd. (JP) 2020-05-27 EP disclosed
US-9468593-B2 Oral composition KABUSHIKI KAISHA SANGI (JP) 2016-10-18 US disclosed
US-20150202128-A1 ORAL COMPOSITION KABUSHIKI KAISHA SANGI (JP) 2015-07-23 US disclosed
EP-2893918-A1 ORAL COMPOSITION Kabushiki Kaisha Sangi (JP) 2015-07-15 EP disclosed
CN-101785863-B Gel-forming composition LINTEC CORP 2013-06-05 CN disclosed
CN-1462194-B Oral preparation and oral preparation holder LINTEC CORP 2013-04-24 CN disclosed
CN-101785863-A Gel-forming composition LINTEC CORP 2010-07-28 CN disclosed
US-20040028724-A1 Pharmaceutical preparation of percutaneous absorption type HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2004-02-12 US disclosed
CN-1462194-A Oral preparation and oral preparation holder LINTEC CORP (JP) 2003-12-17 CN disclosed
EP-1340496-A1 PHARMACEUTICAL PREPARATION OF PERCUTANEOUS ABSORPTION TYPE HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2003-09-03 EP disclosed