Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | SI | P14410 | 3/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FADS1 | O60427 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685052 | 0.91 | PIK3CG (0.74) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL684820 | 0.86 | PIK3CG (0.69) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL683844 | 0.85 | PIK3CG (0.83) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL683742 | 0.85 | KMT2A (0.69) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL1638669 | 0.83 | MAPT (0.64) | KDM4EMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL1638671 | 0.83 | MAPT (0.64) | KDM4EMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL12767404 | 0.83 | MAPT (0.64) | KDM4EMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL1638634 | 0.83 | PIK3CG (0.61) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL1638631 | 0.83 | PIK3CG (0.61) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL12766906 | 0.83 | PIK3CG (0.61) | PIK3CGKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461078-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2013-06-11 | — | — | US | disclosed |
| US-20120107416-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | PIK3CG 2876/4885KDM4E 1473/4885MEN1 536/4885 |
| US-20120107416-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | PIK3CG 2911/4885KDM4E 1286/4885MEN1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.