Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR2 | Q969V1 | 4/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693564 | 0.91 | MCHR2 (0.58) | MCHR2SIGMAR1 | |
| SCHEMBL7382222 | 0.85 | MCHR2 (0.62) | MCHR2SIGMAR1MCHR1 | |
| SCHEMBL13300484 | 0.82 | MCHR2 (0.57) | MCHR2MCHR1 | |
| SCHEMBL3819961 | 0.81 | OPRL1 (0.53) | MCHR2 | |
| SCHEMBL6397901 | 0.80 | MCHR2 (0.53) | MCHR2MCHR1 | |
| SCHEMBL7382052 | 0.80 | MCHR2 (0.58) | MCHR2SIGMAR1MCHR1 | |
| SCHEMBL8012161 | 0.79 | MCHR2 (0.58) | MCHR2MCHR1 | |
| SCHEMBL4408710 | 0.78 | MCHR2 (0.61) | MCHR2SIGMAR1MCHR1 | |
| SCHEMBL8472020 | 0.77 | OXTR (0.57) | MCHR2 | |
| SCHEMBL14445187 | 0.76 | CCR2 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828440-B2 | Analgesics; side effect reduction | EURO-CELTIQUE, S.A. (LU) | 2004-12-07 | — | — | US | claimed |