Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848540 | 0.91 | MCHR2 (0.60) | MCHR2SIGMAR1 | |
| SCHEMBL7382052 | 0.82 | MCHR2 (0.58) | MCHR2SIGMAR1CCR2 | |
| SCHEMBL6397901 | 0.82 | MCHR2 (0.53) | MCHR2CCR2 | |
| SCHEMBL7382222 | 0.82 | MCHR2 (0.62) | MCHR2SIGMAR1 | |
| SCHEMBL8687744 | 0.80 | SIGMAR1 (0.50) | SIGMAR1CCR3OPRM1 | |
| SCHEMBL14273918 | 0.80 | HTR1A (0.52) | — | |
| SCHEMBL13300484 | 0.79 | MCHR2 (0.57) | MCHR2CCR2 | |
| SCHEMBL3819961 | 0.77 | OPRL1 (0.53) | MCHR2OPRM1CCR2 | |
| SCHEMBL7442602 | 0.76 | ADRA1D (0.60) | SIGMAR1CCR3OPRM1 | |
| SCHEMBL3814166 | 0.76 | CCR2 (0.53) | MCHR2OPRM1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807871-A | PSYCHOLOGICAL DISORDERS, ALZHEIMER OR PARKINSON DISEASE | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |