Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.58 |
| ▸ | ACACA | Q13085 | 9/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897971 | 1.00 | ACACB (0.58) | ACACBACACANPY5RNPY1RDRD2 | |
| SCHEMBL6039411 | 0.89 | ACACB (0.69) | ACACBACACANPY5RNPY1R | |
| SCHEMBL6039406 | 0.89 | ACACB (0.69) | ACACBACACANPY5RNPY1R | |
| SCHEMBL8898830 | 0.82 | ACACB (0.81) | ACACBACACANPY5RNPY1RDRD2 | |
| SCHEMBL8898825 | 0.82 | ACACB (0.81) | ACACBACACANPY5RNPY1RDRD2 | |
| SCHEMBL8900995 | 0.82 | ACACB (0.59) | ACACBACACANPY5RNPY1R | |
| SCHEMBL8901000 | 0.82 | ACACB (0.59) | ACACBACACANPY5RNPY1R | |
| SCHEMBL6848680 | 0.80 | ACACB (0.57) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13590717 | 0.79 | ACACB (0.67) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10174793 | 0.78 | SLC6A9 (0.51) | NPY5RNPY1RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |