Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | MMP1 | P03956 | 3/20 | 0.57 |
| ▸ | MMP12 | P39900 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 11/20 | 0.56 |
| ▸ | MMP9 | P14780 | 9/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP14 | P50281 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928657 | 0.90 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4464537 | 0.81 | CA1 (0.70) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL13537908 | 0.79 | CA1 (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6850444 | 0.79 | EGFR (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3928646 | 0.79 | EGFR (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5071025 | 0.79 | PTGS2 (0.82) | CA1CA2CA12CA9CA14 | |
| SCHEMBL15633548 | 0.78 | MMP2 (0.52) | CA1CA2MMP1MMP12GAA | |
| SCHEMBL6848742 | 0.78 | RAPGEF3 (0.59) | CA1CA2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15625449 | 0.77 | PTGS2 (0.63) | CA1CA2MMP1MMP12GAA | |
| SCHEMBL1161379 | 0.77 | EGFR (0.55) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |