Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 18/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848485 | 0.79 | MALT1 (0.59) | MALT1 | |
| SCHEMBL4026247 | 0.70 | PTGS1 (0.76) | MALT1LMNA | |
| SCHEMBL19500958 | 0.69 | MALT1 (0.84) | MALT1 | |
| SCHEMBL10016671 | 0.68 | MALT1 (0.61) | MALT1 | |
| SCHEMBL10016677 | 0.68 | MALT1 (0.66) | MALT1 | |
| SCHEMBL6848788 | 0.68 | MMP1 (0.59) | MALT1LMNA | |
| SCHEMBL23518443 | 0.67 | RAB9A (0.76) | — | |
| SCHEMBL10016672 | 0.67 | MALT1 (0.47) | MALT1LMNA | |
| SCHEMBL13499198 | 0.67 | MALT1 (0.52) | MALT1LMNA | |
| SCHEMBL6848548 | 0.67 | MALT1 (0.49) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020849-A1 | CYTOHESIN INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2011-02-24 | — | — | WO | disclosed |
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |