SCHEMBL6849342

SCHEMBL6849342

O=Cc1ccc(C(F)(F)c2cccc(C=O)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
CYP2A6 P11509 1/20 0.41
NFE2L2 Q16236 1/20 0.41
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
FBP1 P09467 1/20 0.39
UNG P13051 1/20 0.39
TTR P02766 1/20 0.38
PIM1 P11309 1/20 0.38
CISD1 Q9NZ45 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
KIF11 P52732 1/20 0.38
RECQL P46063 1/20 0.37
KDM4E B2RXH2 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
SRC P12931 1/20 0.35
DRD1 P21728 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6854130 0.92 ALDH1A1 (0.48) ALDH1A1CYP2A6NFE2L2POLBL3MBTL1
SCHEMBL28376764 0.91 ALDH1A1 (0.48) ALDH1A1CYP2A6NFE2L2POLBL3MBTL1
SCHEMBL29572467 0.91 ALDH1A1 (0.48) ALDH1A1CYP2A6NFE2L2POLBL3MBTL1
SCHEMBL17508286 0.84 ALDH1A1 (0.54) ALDH1A1CYP2A6POLBL3MBTL1KIF11
SCHEMBL6852179 0.84 CYP2A6 (0.46) ALDH1A1CYP2A6KIF11KDM4EDRD1
SCHEMBL29425705 0.80 FBP1 (0.56) ALDH1A1NFE2L2POLBL3MBTL1FBP1
SCHEMBL67201 0.80 FBP1 (0.56) ALDH1A1NFE2L2POLBL3MBTL1FBP1
SCHEMBL6855120 0.79 ALDH1A1 (0.47) ALDH1A1CYP2A6NFE2L2POLBL3MBTL1
SCHEMBL6853778 0.78 ESR1 (0.48) ALDH1A1CYP2A6NFE2L2UNGKDM4E
SCHEMBL26703563 0.78 ESR1 (0.48) ALDH1A1CYP2A6NFE2L2UNGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6780561-B2 FOR FORMING PROTECTIVE FILM OR AN INSULATING FILM FOR A SEMICONDUCTOR ELEMENT OR A CIRCUIT BOARD SUCH AS A PRINTED BOARD KANSAI PAINT CO., LTD. (JP) 2004-08-24 US disclosed
US-20030143480-A1 For forming protective film or an insulating film for a semiconductor element or a circuit board such as a printed board KANSAI PAINT CO., LTD. (JP) 2003-07-31 US disclosed