SCHEMBL67201

SCHEMBL67201

O=Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.56
NFE2L2 Q16236 1/20 0.55
ALDH1A1 P00352 2/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CISD1 Q9NZ45 2/20 0.49
TTR P02766 1/20 0.49
PIM1 P11309 1/20 0.49
PIM2 Q9P1W9 1/20 0.49
P4HB P07237 1/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
HSP90AA1 P07900 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
CES2 O00748 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425705 1.00 FBP1 (0.56) FBP1NFE2L2ALDH1A1POLBL3MBTL1
Acetaldehyde SCHEMBL28151033 0.94 NFE2L2 (0.54) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL18002652 0.92 NFE2L2 (0.62) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL8702459 0.89 NFE2L2 (0.58) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL6854130 0.87 ALDH1A1 (0.48) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL18002613 0.87 NFE2L2 (0.60) FBP1NFE2L2L3MBTL1P4HBMEN1
SCHEMBL18002587 0.87 NFE2L2 (0.70) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL3392497 0.86 FBP1 (0.45) FBP1NFE2L2ALDH1A1POLBL3MBTL1
SCHEMBL18002753 0.85 NFE2L2 (0.58) FBP1NFE2L2L3MBTL1P4HBMEN1
SCHEMBL6855120 0.85 ALDH1A1 (0.47) FBP1NFE2L2ALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3650 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060333-A High-temperature-resistant silicon rubber and preparation method and application thereof 东莞宏强新材料有限公司 2026-05-19 CN claimed
CN-119977785-A Method for simply synthesizing m-trifluoromethyl cinnamic acid 台州爱申特科技有限公司 2025-05-13 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
US-20240243010-A1 INHIBITOR FOR SELECTIVELY DEPOSITING THIN FILM AND METHOD FOR SELECTIVELY DEPOSITING THIN FILM ADEKA CORPORATION (JP) 2024-07-18 US claimed
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-117867555-A Fluorine-doped carbon quantum dot catalyst for reducing methane by high-efficiency electrocatalytic carbon dioxide, and preparation method and application thereof 上海大学 2024-04-12 CN claimed
CN-116283821-B Phencyclized propylamine compound, preparation method and application 郑州大学 2024-01-26 CN claimed
US-4301167-A ANTIINFLAMMATORY AGENTS, ANALGESICS INSTITUT MERIEUX (FR) 1981-11-17 US claimed
US-4271319-A Phenyl beta-chloro-alpha-hydroxy-beta-(3-trifluoromethylphenyl)ethyl ketone and process for its production HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-06-02 US claimed
US-4240823-A New plant growth regulating compositions which contain derivatives of N-acyl methionine PHILAGRO S.A. (FR) 1980-12-23 US claimed
US-4229378-A Process for the production of 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanone HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-10-21 US claimed
US-4212998-A 1-Phenyl-3-(3-trifluoromethylphenyl)-2-propanol and process for its production HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-15 US claimed
US-4212999-A 1-Phenyl-3-(3-trifluoromethylphenyl)-1,2-propane diol and process for its production HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-15 US claimed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed