Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 7/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762408 | 0.90 | MIF (0.52) | TRPA1TRPV1MIFALDH1A1CYP3A4 | |
| SCHEMBL3246197 | 0.84 | TRPA1 (0.43) | TRPA1TRPV1MIFALDH1A1CYP3A4 | |
| SCHEMBL8763223 | 0.78 | MIF (0.48) | TRPA1TRPV1MIFALDH1A1CYP3A4 | |
| SCHEMBL21753640 | 0.77 | TSHR (0.35) | CYP3A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL5710769 | 0.77 | TSHR (0.35) | CYP3A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL30350978 | 0.69 | TRPA1 (0.65) | TRPA1TRPV1MIFALDH1A1 | |
| SCHEMBL12804676 | 0.69 | CYP3A4 (0.55) | TRPA1P2RY6CYP3A4SLC6A2SLC6A3 | |
| SCHEMBL4700599 | 0.69 | MIF (0.56) | MIFALDH1A1TAAR1 | |
| SCHEMBL21056125 | 0.68 | SLC6A2 (0.48) | HPGDTAAR1SLC6A2SLC6A3 | |
| SCHEMBL1893546 | 0.68 | SIGMAR1 (0.47) | TRPA1CYP3A4TAAR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777494-B1 | POLYTHIOURETHANE AND POLYTHIOETHER POLYMERS FORMED MAY BE USED ALONE OR MIXED FOR OPTICAL PURPOSES SUCH AS THE MANUFACTURE OF OPHTHALMIC LENSES | OPTIMA INC. | 2004-08-17 | — | — | US | disclosed |
| EP-0349195-B1 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5629394-A | ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED | EXXON CHEMICAL PATENTS INC (US) | 1997-05-13 | — | — | US | disclosed |
| US-5444135-A | Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously | EXXON CHEMICAL PATENTS INC. (US) | 1995-08-22 | — | — | US | disclosed |
| US-5336745-A | Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators | EXXON CHEMICAL PATENTS INC. (US) | 1994-08-09 | — | — | US | disclosed |
| US-5032653-A | Catalysts | EXXON CHEMICAL PATENTS, INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0349195-A2 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-03 | — | — | EP | disclosed |