Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51201 | 0.84 | FFAR3 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7347647 | 0.83 | ALDH1A1 (0.43) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8053454 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3673385 | 0.81 | ALDH1A1 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28746064 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4382923 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL104624 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17818653 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9489101 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4882973 | 0.81 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790879-B2 | A JET PRINTING INK CONTAINING A DYE AND AN AQUEOUS MEDIUM, AND A BASIC POLYMER HAVING SIDE-CHAIN CONTAINING A TERTIARY AMINO GROUP, A QUATERNARY AMMONIUM GROUP OR NITROGEN ATOM-CONTAINING HETEROCYCLIC GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20030065052-A1 | JET PRINTING INK AND INK-JET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2003-04-03 | — | — | US | disclosed |