SCHEMBL7347647

SCHEMBL7347647

CCC(CC)(C(=O)O)C(=O)CCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
LMNA P02545 2/20 0.43
EGLN1 Q9GZT9 2/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
SUCNR1 Q9BXA5 1/20 0.43
FFAR3 O14843 2/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
SLC15A2 Q16348 1/20 0.40
AKR1B1 P15121 1/20 0.37
GPR84 Q9NQS5 7/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 7/20 0.36
PPARA Q07869 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31066793 0.86 SLC22A6 (0.48) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL994717 0.83 HDAC3 (0.43) ALDH1A1MEN1KMT2ACYP1A2THRB
Succinic Acid SCHEMBL6849896 0.83 FFAR3 (0.50) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL1615829 0.81 HDAC3 (0.42) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL380753 0.78 LDHA (0.38) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL11305844 0.78 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL13545111 0.77 FFAR3 (0.40) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL51201 0.76 FFAR3 (0.41) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL29152693 0.76 FAAH (0.55) ALDH1A1MEN1KMT2ACYP1A2GPR84
SCHEMBL29159521 0.76 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150225329-A1 ALTERNATIVE PATHWAYS TO ADIPIC ACID BY COMBINED FERMENTATION AND CATALYTIC METHODS BIOAMBER INC. 2015-08-13 US disclosed
EP-2895613-A2 ALTERNATIVE PATHWAYS TO ADIPATES AND ADIPIC ACID BY COMBINED FERMENTATION AND CATALYTIC METHODS BioAmber Inc. (US) 2015-07-22 EP disclosed
CN-104603277-A Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods BIOAMBER SAS 2015-05-06 CN disclosed
WO-2014043182-A2 ALTERNATIVE PATHWAYS TO ADIPATES AND ADIPIC ACID BY COMBINED FERMENTATION AND CATALYTIC METHODS BIOAMBER INC. (US) 2014-03-20 WO disclosed
EP-0542708-B1 Substituted beta-amino acid derivatives useful as platelet aggregation inhibitors MONSANTO CO (US) 2001-05-30 EP disclosed
US-5973003-A TREATMENT OF THROMBOSIS, STROKE, MYOCARDIAL INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS G. D. SEARLE & CO. (US) 1999-10-26 US disclosed
US-5703125-A MELT BLEND OF SOAP, SURFACTANT AND SOLVENT G. D. SEARLE & CO. (US) 1997-12-30 US disclosed
EP-0614360-B1 SUBSTITUTED BETA-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1997-03-19 EP disclosed
EP-0614360-A1 SUBSTITUTED -g(b)-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. SEARLE & CO (US) 1994-09-14 EP disclosed
US-5344957-A Amidinoiphenyl-substituted G.D. SEARLE & CO. (US) 1994-09-06 US disclosed
US-5239113-A Anticoagulants MONSANTO COMPANY (US) 1993-08-24 US disclosed
EP-0542708-A1 Substituted B-amino acid derivatives useful as platelet aggregation inhibitors MONSANTO COMPANY (US) 1993-05-19 EP disclosed
WO-1993007867-A1 SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1993-04-29 WO disclosed
EP-0063323-B1 5-SUBSTITUTED 4-OXO-PGI1 DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1985-10-30 EP disclosed
US-4520018-A 5-Substituted-4-oxo-PGI1 derivatives, PGI1 compounds of similar structure, their pharmaceutical methods and process for the preparation of said compounds CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1985-05-28 US disclosed
EP-0063323-A1 5-Substituted 4-oxo-PGI1 derivatives, their preparation and pharmaceutical compositions CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1982-10-27 EP disclosed