SCHEMBL6849939

SCHEMBL6849939

C#Cc1ccccc1-c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 5/20 0.48
ALOX12 P18054 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALOX15 P16050 2/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
MAPT P10636 5/20 0.41
CYP3A4 P08684 4/20 0.41
HPGD P15428 3/20 0.41
HTT P42858 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757877 0.82 CYP2A6 (0.44) ALDH1A1HSD17B10L3MBTL1TDP1MAPK1
SCHEMBL1302811 0.82 CYP2A6 (0.48) ALDH1A1HSD17B10TDP1MAPK1CYP3A4
SCHEMBL29159006 0.80 CYP2A6 (0.46) ALDH1A1HSD17B10TDP1MAPK1PTGS2
SCHEMBL12367620 0.78 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL6517747 0.76 ESR2 (0.42) CYP1A2CYP2C9ESR2
SCHEMBL12367621 0.75 ALDH1A1 (0.60) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL6512088 0.75 ESR2 (0.41) ESR2
SCHEMBL29588993 0.75 CYP3A4 (0.44) ALDH1A1HSD17B10TSHRTDP1MAPT
SCHEMBL651587 0.75 ALDH1A1 (0.44) ALDH1A1TSHRTDP1MAPK1MAPT
SCHEMBL7932862 0.75 ESR2 (0.41) ALDH1A1ALOX12L3MBTL1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682782-B2 TRANSISTORS, LIQUID CRYSTAL DISPLAY, ELECTROOPTICS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-01-27 US disclosed
EP-1170273-B1 Alkynic compounds, their use as monomers in vacuum deposition polymerisation, thin films formed from these polymers and their use in electroluminescent devices KOREA RES INST CHEM TECH (KR) 2003-05-28 EP disclosed
US-20020018912-A1 Organic compound having an acetylene group, vacuum deposition polymerization thereof, deposited polymerized thin film, and electroluminescence device containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-02-14 US disclosed
EP-1170273-A1 Alkynic compounds, their use as monomers in vacuum deposition polymerisation, thin films formed from these polymers and their use in electroluminescent devices KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-01-09 EP disclosed