Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.74 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2271950 | 0.98 | LOXL2 (0.72) | LOXL2HTR2AHTR1DRAB9ANPC1 | |
| SCHEMBL11806220 | 0.86 | LOXL2 (0.54) | LOXL2HTR2AHTR1DDAOCA12 | |
| SCHEMBL31406127 | 0.86 | LOXL2 (0.54) | LOXL2HTR2AHTR1DDAOCA12 | |
| SCHEMBL19953415 | 0.85 | LOXL2 (1.00) | LOXL2RAB9ANPC1PIN1DAO | |
| SCHEMBL865051 | 0.85 | LOXL2 (0.72) | LOXL2RAB9ANPC1PIN1DAO | |
| SCHEMBL8296766 | 0.79 | LOXL2 (0.70) | LOXL2RAB9ANPC1PIN1DAO | |
| SCHEMBL11811160 | 0.79 | IDO1 (0.49) | LOXL2HTR2ADAOKDM4EALDH1A1 | |
| SCHEMBL31190977 | 0.79 | CYP1A2 (0.47) | LOXL2HTR2AHTR1DHSD17B10MAPT | |
| SCHEMBL6803154 | 0.78 | LOXL2 (0.77) | LOXL2HTR2AHTR1DRAB9ANPC1 | |
| SCHEMBL3052921 | 0.78 | LOXL2 (0.58) | LOXL2RAB9ANPC1PIN1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |
| WO-2011024078-A1 | 3 -OXOPIPERAZINIUM DERIVATIVES AS AGONISTS OF NERVE GROWTH FACTOR AND THEIR USE AS MEDICAMENTS | INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PII SUNYER (IDIBAPS) (ES) | 2011-03-03 | — | — | WO | disclosed |
| EP-2289882-A1 | 3-oxopiperazinium derivatives as agonists of nerve growth factor and their use as medicaments | Institut d'Investigacions Biomédiques August PI I Sunyer (ES) | 2011-03-02 | — | — | EP | disclosed |