Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765258 | 0.92 | OPRM1 (0.41) | OPRM1CACNA1COPRD1OPRK1 | |
| SCHEMBL6850630 | 0.90 | MEN1 (0.41) | OPRM1ALDH1A1CACNA1COPRD1OPRK1 | |
| SCHEMBL7160989 | 0.88 | OPRM1 (0.49) | OPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL6771752 | 0.87 | OPRM1 (0.39) | OPRM1ALDH1A1CXCR2 | |
| SCHEMBL6766826 | 0.87 | CACNA1C (0.48) | OPRM1CACNA1COPRD1OPRK1 | |
| SCHEMBL6766817 | 0.86 | OPRM1 (0.37) | OPRM1CACNA1COPRD1OPRK1CXCR2 | |
| SCHEMBL6767228 | 0.81 | USP2 (0.39) | OPRM1ALDH1A1CACNA1COPRD1OPRK1 | |
| SCHEMBL7160833 | 0.79 | KMT2A (0.44) | OPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL27445509 | 0.79 | ALDH1A1 (0.38) | OPRM1ALDH1A1CXCR2 | |
| SCHEMBL6766373 | 0.77 | KMT2A (0.41) | OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| CN-1099420-C | Substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives, methods of preparing them and their use as pest-control agents | BAYER AG (DE) | 2003-01-22 | — | — | CN | disclosed |
| US-5981567-A | ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| CN-1126475-A | Substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives, methods of preparing them and their use as pest-control agents | BAYER AG (DE) | 1996-07-10 | — | — | CN | disclosed |