Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160833 | 0.91 | KMT2A (0.44) | OPRM1OPRD1OPRK1ALDH1A1ALOX15 | |
| SCHEMBL6850209 | 0.88 | OPRM1 (0.40) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL6771752 | 0.85 | OPRM1 (0.39) | OPRM1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6765258 | 0.80 | OPRM1 (0.41) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL6850630 | 0.79 | MEN1 (0.41) | OPRM1OPRD1OPRK1ALDH1A1KDM4E | |
| SCHEMBL6766826 | 0.78 | CACNA1C (0.48) | OPRM1OPRD1OPRK1 | |
| SCHEMBL27445509 | 0.76 | ALDH1A1 (0.38) | OPRM1ALDH1A1KDM4E | |
| SCHEMBL6765932 | 0.75 | S1PR5 (0.43) | OPRM1 | |
| SCHEMBL6766373 | 0.75 | KMT2A (0.41) | OPRM1ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6766817 | 0.75 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |