Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160842 | 0.91 | KMT2A (0.44) | MEN1RAB9AKMT2AOPRM1OPRD1 | |
| SCHEMBL6850215 | 0.89 | OPRM1 (0.45) | OPRM1OPRD1CACNA1COPRK1KCNH2 | |
| SCHEMBL6766377 | 0.88 | CYP2D6 (0.43) | MEN1RAB9AKMT2AOPRM1OPRD1 | |
| SCHEMBL6762143 | 0.80 | MEN1 (0.39) | MEN1RAB9AKMT2AOPRM1CYP2D6 | |
| SCHEMBL6771757 | 0.77 | OPRM1 (0.41) | KMT2AOPRM1OPRD1CACNA1COPRK1 | |
| SCHEMBL6850630 | 0.75 | MEN1 (0.41) | MEN1RAB9AKMT2AOPRM1OPRD1 | |
| SCHEMBL9466532 | 0.71 | OPRM1 (0.54) | OPRM1OPRD1CACNA1COPRK1 | |
| SCHEMBL9467323 | 0.71 | OPRD1 (0.77) | MEN1KMT2AOPRM1OPRD1CACNA1C | |
| SCHEMBL6767228 | 0.71 | USP2 (0.39) | MEN1RAB9AKMT2AOPRM1OPRD1 | |
| SCHEMBL9466400 | 0.70 | OPRD1 (0.56) | OPRM1OPRD1CACNA1COPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-5981567-A | ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |