Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | HTR1D | P28221 | 1/20 | 0.74 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849557 | 0.98 | HTR1B (0.88) | HTR1BL3MBTL1HTR1DKCNA3DRD2 | |
| SCHEMBL1109801 | 0.92 | HTR1B (1.00) | HTR1BL3MBTL1HTR1DKCNA3DRD2 | |
| SCHEMBL10675449 | 0.89 | L3MBTL1 (0.71) | HTR1BL3MBTL1HTR1DKCNA3HDAC3 | |
| SCHEMBL7370368 | 0.86 | L3MBTL1 (0.77) | HTR1BL3MBTL1HTR1DTP53CYP1A2 | |
| SCHEMBL595753 | 0.85 | HTR1B (1.00) | HTR1BL3MBTL1HTR1DKCNA3DRD2 | |
| Hydrochloric Acid SCHEMBL7372065 | 0.85 | L3MBTL1 (0.74) | HTR1BL3MBTL1HTR1DTP53CYP1A2 | |
| SCHEMBL13886634 | 0.85 | HTR1B (0.85) | HTR1BL3MBTL1HTR1DKCNA3DRD2 | |
| SCHEMBL11894925 | 0.83 | DRD2 (0.80) | HTR1BKCNA3DRD2DRD4DRD3 | |
| Iodide SCHEMBL30481083 | 0.83 | HTR1B (0.96) | HTR1BL3MBTL1HTR1DKCNA3DRD2 | |
| Hydrochloric Acid SCHEMBL10921722 | 0.83 | HTR1B (0.96) | HTR1BL3MBTL1HTR1DKCNA3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | claimed |
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-6756384-B2 | TREATMENT OF DISEASES AND DISORDERS RELATED TO THE HISTAMINE H3 RECEPTOR. | NOVO NORDISK A/S (DK) | 2004-06-29 | — | — | US | disclosed |
| US-20030135056-A1 | Imidazole compounds | HIGH POINT PHARMACEUTICALS, LLC | 2003-07-17 | — | — | US | disclosed |
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| US-6437147-B1 | FOR THERAPY OF DISEASES OF CENTRAL NERVOUS SYSTEM, PERIPHERAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGICAL SYSTEM | NOVO NORDISK (DK) | 2002-08-20 | — | — | US | disclosed |
| US-20020058659-A1 | Imidazole compounds | HIGH POINT PHARMACEUTICALS, LLC | 2002-05-16 | — | — | US | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135056-A1 | Imidazole compounds | HRH3, HRH4, HRH2 | HTR1B 114/4885L3MBTL1 3041/4885HTR1D 146/4885 |
| US-20020058659-A1 | Imidazole compounds | HRH3, HRH4, HRH2 | HTR1B 114/4885L3MBTL1 3041/4885HTR1D 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.