Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | HTR1B | P28222 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7372065 | 0.98 | L3MBTL1 (0.74) | L3MBTL1HTR1BRAB9AMEN1KMT2A | |
| SCHEMBL10801216 | 0.93 | HTR1B (0.73) | L3MBTL1HTR1BRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10801430 | 0.92 | HTR1B (0.71) | L3MBTL1HTR1BRAB9AMEN1KMT2A | |
| SCHEMBL6850933 | 0.86 | HTR1B (0.85) | L3MBTL1HTR1BMEN1KMT2AKDM4E | |
| SCHEMBL7036584 | 0.86 | MGLL (0.67) | L3MBTL1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL6849557 | 0.84 | HTR1B (0.88) | L3MBTL1HTR1BMEN1KMT2AKDM4E | |
| SCHEMBL10875500 | 0.84 | BCHE (0.70) | L3MBTL1MEN1KMT2ALTA4HSIGMAR1 | |
| SCHEMBL10675449 | 0.83 | L3MBTL1 (0.71) | L3MBTL1HTR1BMEN1KMT2AKDM4E | |
| SCHEMBL10818227 | 0.83 | RAB9A (0.65) | L3MBTL1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10818054 | 0.83 | RAB9A (0.65) | L3MBTL1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724577-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011238-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | claimed |
| EP-0724577-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011238-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |