Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851542 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL50100 | 0.83 | CYP1A2 (0.43) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL3840461 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDCYP1A2TSHR | |
| Ammonia Solution, Strong SCHEMBL8665916 | 0.82 | CYP1A2 (0.42) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL3747912 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL21809379 | 0.80 | HPRT1 (0.56) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| Trimethylammonium SCHEMBL5191404 | 0.78 | CYP1A2 (0.39) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL20435263 | 0.78 | MAPT (0.59) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL2783372 | 0.78 | HSD17B10 (0.48) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL11047499 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDCYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777111-B1 | HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE | KABUSHIKI KAISHA CHUO KENKYUSHO (JP) | 2004-08-17 | — | — | US | disclosed |