Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556331 | 0.83 | HTR1B (0.48) | ALDH1A1HSD17B10HPGDCYP1A2TSHR | |
| SCHEMBL1449787 | 0.83 | HTR1B (0.48) | ALDH1A1HSD17B10HPGDCYP1A2TSHR | |
| SCHEMBL3747912 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL20435263 | 0.78 | MAPT (0.59) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL2783372 | 0.78 | HSD17B10 (0.48) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL6865702 | 0.76 | HTR1B (0.43) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL6851541 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL10929913 | 0.74 | KCNA3 (0.51) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL21381123 | 0.73 | KCNA3 (0.46) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL26445243 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDCYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043185-B1 | METHOD FOR PRODUCTION OF TITANIUM HALIDE CATALYST COMPONENT, CATALYST SYSTEM INCLUDING SUCH COMPONENT, AND POLYMERIZATION OF ALPHA-OLEFINS USING SUCH SYSTEM | STAUFFER CHEMICAL COMPANY (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0012397-B1 | POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING ALPHA-OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4379898-A | MAGNESIUM METAL, ORGANIC HALIDE, TITANIUM TETRAHALIDE, TRIARYL PHOSPHITE AND ALUMINUM HALIDE | PHILLIPS PETROLEUM COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
| US-4347160-A | Titanium halide catalyst system | STAUFFER CHEMICAL COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4325836-A | Novel titanium halide containing catalyst | STAUFFER CHEMICAL COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0044445-A2 | Titanium halide containing catalyst | STAUFFER CHEMICAL COMPANY (US) | 1982-01-27 | — | — | EP | disclosed |
| EP-0043185-A1 | Method for production of titanium halide catalyst component, catalyst system including such component, and polymerization of alpha-olefins using such system | STAUFFER CHEMICAL COMPANY (US) | 1982-01-06 | — | — | EP | disclosed |
| US-4287091-A | PREPARED BY MILLING MAGNESIUM, AN ORGANIC HALIDE, AND TITANIUM TETRAHALIDE | PHILLIPS PETROLEUM CO. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4276192-A | Polymerization catalysts | PHILLIPS PETROLEUM COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| US-4260708-A | REPLACING A PORTION OF TRIALKYLALUMINUM ACTIVATOR WITH DIALKYLALUMINUM DIALKYLPHOSPHATE | PHILLIPS PETROLEUM COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4243552-A | MAGNESIUM CHLORIDE OR MANGANESE CHLORIDE AND ADJUVANT | PHILLIPS PETROLEUM COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4237029-A | HEAT TREATMENT AFTER MILLING; FOR POLYMERIZATION OF PROPYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4130503-A | MAGNESIUM CHLORIDE, TITANIUM CHLORIDE, ALUMINUM CHLORIDE | PHILLIPS PETROLEUM COMPANY (US) | 1978-12-19 | — | — | US | disclosed |