Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | ITGAV | P06756 | 15/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851727 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BITGAVL3MBTL1ITGB1 | |
| Ethyl Acetate SCHEMBL9842134 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BITGAVL3MBTL1ITGB1 | |
| SCHEMBL9191989 | 0.89 | BMP1 (0.44) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Hydrochloric Acid SCHEMBL9188432 | 0.88 | BMP1 (0.43) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL4959733 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BL3MBTL1 | |
| SCHEMBL1509780 | 0.84 | AVPR1B (0.54) | ITGB3ITGA2BBMP1 | |
| SCHEMBL1509781 | 0.84 | AVPR1B (0.54) | ITGB3ITGA2BBMP1 | |
| SCHEMBL7898282 | 0.84 | AVPR1B (0.54) | ITGB3ITGA2BBMP1 | |
| SCHEMBL30007346 | 0.84 | AVPR1B (0.54) | ITGB3ITGA2BBMP1 | |
| SCHEMBL9842188 | 0.84 | NR3C1 (0.46) | ITGB3ITGA2BITGAVL3MBTL1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942900-A4 | STEREOSPECIFIC PREPARATION OF CHIRAL 1-ARYL- AND 1-HETEROARYL-2-SUBSTITUTED ETHYL-2-AMINES | AVENTIS PHARM PROD INC (US) | 2004-08-04 | — | — | EP | disclosed |
| US-6433172-B1 | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS | AVENTIS PHARMACEUTICALS INC. | 2002-08-13 | — | — | US | disclosed |
| EP-0942900-A1 | STEREOSPECIFIC PREPARATION OF CHIRAL 1-ARYL- AND 1-HETEROARYL-2-SUBSTITUTED ETHYL-2-AMINES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998011064-A1 | STEREOSPECIFIC PREPARATION OF CHIRAL 1-ARYL- AND 1-HETEROARYL-2-SUBSTITUTED ETHYL-2-AMINES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-19 | — | — | WO | disclosed |