Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685159 | 0.89 | NPC1 (0.70) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL14026534 | 0.88 | MAPT (0.67) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL684716 | 0.88 | NPC1 (0.67) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL683991 | 0.88 | NPC1 (0.65) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL683996 | 0.88 | RAB9A (0.81) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL684848 | 0.88 | NPC1 (0.75) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9921039 | 0.86 | MAPT (0.65) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL684760 | 0.86 | MAPT (0.62) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL6570260 | 0.86 | NPC1 (0.77) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL685119 | 0.86 | NPC1 (0.77) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | NPC1 1690/4885RAB9A 3846/4885MAPT 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.