Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | BBOX1 | O75936 | 7/20 | 0.34 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL36781 | 0.98 | CA4 (0.76) | CA4BBOX1SLC22A16CPT2CPT1A | |
| Citric Acid SCHEMBL7083474 | 0.95 | CA4 (0.73) | CA4BBOX1SLC22A16CPT2CPT1A | |
| Citric Acid SCHEMBL5471628 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL445486 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL107472 | 0.89 | CA4 (0.64) | CA4BBOX1CPT2 | |
| Citric Acid SCHEMBL379041 | 0.87 | CA4 (0.84) | CA4 | |
| Citric Acid SCHEMBL7519368 | 0.87 | CA4 (0.84) | CA4 | |
| Citric Acid SCHEMBL5077427 | 0.87 | CA4 (0.84) | CA4 | |
| Citric Acid SCHEMBL21569395 | 0.87 | CA4 (0.84) | CA4 | |
| Citric Acid SCHEMBL21569386 | 0.87 | CA4 (0.84) | CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708452-B1 | Ion-conductive polymer electrolyte, method for producing the electrolyte and capacitors using the electrolyte | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-0708452-A1 | Ion-conductive polymer electrolyte, method for producing the electrolyte and capacitors using the electrolyte | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |