Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | BBOX1 | O75936 | 7/20 | 0.34 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL36781 | 0.98 | CA4 (0.76) | CA4BBOX1SLC22A16CPT2CPT1A | |
| Citric Acid SCHEMBL6852203 | 0.95 | CA4 (0.73) | CA4BBOX1SLC22A16CPT2CPT1A | |
| Citric Acid SCHEMBL28215288 | 0.90 | CA4 (0.90) | CA4 | |
| Citric Acid SCHEMBL3277654 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL20668544 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL23012792 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL28062573 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL21555662 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL338469 | 0.90 | CA4 (0.89) | CA4 | |
| Citric Acid SCHEMBL317585 | 0.90 | CA4 (0.89) | CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030224958-A1 | Solutions for cleaning polished aluminum-containing layers | ANDREAS MICHAEL T (US) | 2003-12-04 | — | — | US | disclosed |
| US-6635562-B2 | Methods and solutions for cleaning polished aluminum-containing layers | MICRON TECHNOLOGY, INC. | 2003-10-21 | — | — | US | disclosed |
| US-20010023127-A1 | Methods and solutions for cleaning polished aluminum-containing layers, methods for making metallization structures, and the structures resulting from these methods | CONVERSANT INTELLECTUAL PROPERTY MANAGEMENT INC. (CA) | 2001-09-20 | — | — | US | disclosed |
| US-6265781-B1 | Methods and solutions for cleaning polished aluminum-containing layers, methods for making metallization structures, and the structures resulting from these methods | MICRON TECHNOLOGY, INC. | 2001-07-24 | — | — | US | disclosed |