SCHEMBL6852259

SCHEMBL6852259

O=C(OC(=O)c1ccccc1Cl)c1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.60
RAB9A P51151 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
NPC1 O15118 1/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NR4A1 P22736 1/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.46
MGLL Q99685 1/20 0.46
MIF P14174 1/20 0.44
POLB P06746 2/20 0.44
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153557 0.89 SMN1; SMN2 (0.58) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL6857236 0.88 KMT2A (0.49) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL19875699 0.88 RAB9A (0.55) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL19875700 0.88 RAB9A (0.55) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL2153551 0.87 CES2 (0.62) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL29111430 0.83 UTS2R (0.48) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL247591 0.83 CES2 (0.65) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL28775846 0.82 CES2 (0.59) HPGDRAB9ASMN1; SMN2CES2CES1
SCHEMBL247590 0.82 CES2 (0.59) HPGDRAB9ASMN1; SMN2CES2CES1
Biphenyl SCHEMBL3127994 0.79 CES2 (0.55) RAB9ASMN1; SMN2CES2CES1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746812-B2 USING A FLUORINE-CONTAINING POLYMER IN THE PHOTOSENSITIVE RESIN COMPOSITION TO GIVE HIGH CONTRAST OF PRINTING PLATE IMAGE WHILE MAINTAINING PRESS LIFE FUJI PHOTO FILM CO., LTD. (JP) 2004-06-08 US disclosed
US-20020051929-A1 Using a fluorine-containing polymer in the photosensitive resin composition to give high contrast of printing plate image while maintaining press life FUJIFILM CORPORATION (JP) 2002-05-02 US disclosed