Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 16/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | MMP3 | P08254 | 1/20 | 0.68 |
| ▸ | MMP1 | P03956 | 4/20 | 0.63 |
| ▸ | IDE | P14735 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852613 | 0.90 | FCER2 (0.74) | FCER2MMP9MMP3MMP1IDE | |
| SCHEMBL6852364 | 0.79 | FCER2 (0.81) | FCER2MMP9MMP3MMP1 | |
| SCHEMBL6852647 | 0.77 | FCER2 (0.77) | FCER2MMP9MMP3MMP1 | |
| SCHEMBL6851903 | 0.75 | FCER2 (1.00) | FCER2MMP9MMP3MMP1IDE | |
| SCHEMBL20335073 | 0.75 | MEN1 (0.61) | MMP3POLB | |
| SCHEMBL18292346 | 0.74 | HPGDS (0.70) | POLB | |
| SCHEMBL14432427 | 0.73 | POLB (0.53) | POLB | |
| SCHEMBL7406329 | 0.73 | MMP1 (0.80) | FCER2MMP9MMP3MMP1 | |
| SCHEMBL4982001 | 0.72 | CTSB (0.67) | POLB | |
| SCHEMBL15851264 | 0.71 | FCER2 (0.62) | FCER2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011181-A1 | PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AMICUS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |