Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896448 | 0.83 | PDE10A (0.47) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL525672 | 0.79 | PDE10A (0.50) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| Anthracene SCHEMBL27918023 | 0.77 | NQO2 (0.43) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL6852382 | 0.76 | RAB9A (0.50) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL6852218 | 0.76 | RAB9A (0.50) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL3559408 | 0.75 | PDE10A (0.47) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL27321431 | 0.75 | PDE10A (0.47) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL97699 | 0.75 | ALDH1A1 (0.47) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL5845185 | 0.75 | PDE10A (0.47) | PDE10ARAB9ANPC1SMN1; SMN2PIM1 | |
| SCHEMBL1472894 | 0.73 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |